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Vaccine-preventable hepatitis (VPH) includes hepatitis A and hepatitis B.
Hepatitis C is not vaccine preventable. |
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Travelers can acquire VPH through many modes of transmission[3-8]
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HAV is one of the world's most common vaccine-preventable diseases[3]
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- Annually, millions of American travelers visit countries rated by the Centers for Disease Control and Prevention (CDC) as intermediate to high risk for hepatitis A[1,4]
- Risk for infection increases with duration of travel and is highest for those visiting rural and "back-country" areas[5]
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The risk for HBV can be 100 times greater than HIV[6]
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- 10%–15% of travelers come into contact with blood or other body fluids[7]
- Contaminated needles cause >3 times more HBV infections (8 to 16 million) than hepatitis C virus or HIV infections worldwide each year[8]
- 25%–30% of HBV infections come from an unknown source[3]
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Important Safety Information:
TWINRIX is contraindicated in people with hypersensitivity to any component of the vaccine, including yeast and neomycin.
In clinical trials with TWINRIX, the most common solicited adverse events were:
soreness at the injection site
redness at the injection site
headache
fatigue
They were mild and self-limiting and did not last more than 48 hours.
As with any vaccine, rare adverse events may occur. (See Adverse Reactions
section of the Prescribing Information for TWINRIX for other potential side effects.)
As with any vaccine, TWINRIX may not protect 100% of individuals receiving the vaccine.
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